Markus Buehler
Jerry McAfee (1940) Professor in Engineering and Professor of Civil and Environmental Engineering, Department of Civil and Environmental Engineering

Who they work with
Markus Buehler is the Jerry McAfee (1940) Professor in Engineering and Professor of Civil and Environmental Engineering in MIT’s Department of Civil and Environmental Engineering. He is also a member of the Laboratory for Atomistic and Molecular Mechanics, Center for Materials Science and Engineering, and Center for Computational Engineering. His research focuses on making bio‐inspired nanotechnology sustainable and scalable for large‐volume materials applications. He is interested in natural, biological, and synthetic materials, their mechanical, thermal, and optical properties, and biologically-inspired material design, from atoms to structures. He is especially interested in natural materials like collagen, bone, and spider silk that offer sustainable, mechanical functions.
Selected Publications
- Ni, B., Kaplan, D.L., Buehler, M.J. (2023). Generative design of de novo proteins based on secondary-structure constraints using an attention-based diffusion model. Chem https://doi.org/10.1016/j.chempr.2023.03.020
- Buehler, M. J., 2023, “Unsupervised Cross-Domain Translation Via Deep Learning and Adversarial Attention Neural Networks and Application to Music-Inspired Protein Designs,” Patterns, 4(3), p. 100692.
- Milazzo, M., Muyshondt, P. G. G., Carstensen, J., Dirckx, J. J. J., Danti, S., Buehler, M. J. (2020). De novo topology optimization of total ossicular replacement prostheses. Journal of the Mechanical Behavior of Biomedical Materials, vol. 103, p. 103541.
- CH Yu, C.H., Buehler, M. J. (2020). Sonification based de novo protein design using artificial intelligence, structure prediction, and analysis using molecular modeling. APL Bioengineering 4 (1), 016108.
Media
- May 1, 2021: The Academic Times, Machine learning could yield protein-based coatings that curb food waste.
- April 3, 2020: Science Magazine, Scientists have turned the structure of the coronavirus into music.
- November 22, 2019: MIT News, Forum addresses future of civil and environmental engineering education.
- June 26, 2019: MIT News, Translating proteins into music, and back.
- March 1, 2019: MIT News, Spider silk could be used as robotic muscle.
- June 14, 2017: Smithsonian Magazine, This Conch-Shell Inspired Material Could Make Helmets and Body Armor Safer.